June 18, 2013 05:12 UTC

Health

A Campaign Against Alzheimer's Disease

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Alzheimer's patient and caregiver.Alzheimer's patient and caregiver.
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Alzheimer's patient and caregiver.
Alzheimer's patient and caregiver.

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This is the VOA Special English Health Report.
 
Last week, the United States government announced a major education and research campaign against Alzheimer's disease. The brain-wasting disease has no cure. The plan includes more efforts to develop drugs to prevent it.

Download PDF: A Campaign Against Alzheimer's Disease
 
In the United States, more than five million people have Alzheimer's or some other form of dementia. As the population gets older, the number is expected to reach almost eight million by twenty-thirty. By then, experts say Alzheimer's and other dementia disorders could affect as many as sixty-six million people worldwide.
 
The national Alzheimer's plan calls on scientists to develop treatments to prevent the disease by twenty twenty-five. Officials at the National Institutes of Health have promised fifty million dollars to help support that effort. NIH held a conference of the nation's top Alzheimer's researchers where NIH Director Francis Collins discussed the plan.
 
FRANCIS COLLINS: "We have learned more about this disease in the last couple of years than probably ever before. And now the goal is to take that and translate it into interventions."
 
Early next year, scientists at the Banner Alzheimer's Institute in Arizona plan to begin human testing of an experimental drug. The drug is called crenezumab, and the hope is it will prevent Alzheimer's.
 
The study will involve members of a large extended family living in villages in the Medellin area in Colombia. Some of the family members have a rare genetic disorder that causes them to get early-onset Alzheimer's. They begin to show signs of mental loss in their mid-forties and fully develop the disease by their early fifties.
 
Three hundred people have agreed to be in the study. One-third of them will receive crenezumab. The others will be given a placebo, a pill that does not contain any drug. They will not know if they have been given the drug or the placebo. The study will also include a smaller number of people in the United States.
 
Pierre Tariot will help lead the study, known as a human trial. He says all of the people have been informed that the drug might not work or that they might receive a placebo. Mr. Tariot says the people still wanted to be in the study.
 
PIERRE TARIOT: "They have been faced with this devastating illness hitting every generation for hundreds of years. As one of them put it, 'There are many rivers to cross but at least we're at the first bank.'  And that's kind of the attitude that people have had."
 
Scientists hope that if the drug works in those facing early-onset Alzheimer's, then it might also help older people.
 
The study in Colombia could take as long as five years, but researchers believe they could get results in two years.
 
And that's the VOA Special English Health Report. You can learn more about Alzheimer's disease and find a link to the national plan at voaspecialenglish.com. I'm Faith Lapidus.
 
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Contributing: Jessica Berman

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by: hisk from: japan
06/03/2012 9:47 AM
Now, there are many elderly people in japan.
Of course, Alzheimer's elderly should be many.
We may become Alzheimerv several decades later, too.
If the study succeeds,many people around the world will be saved.I hope that this study will successful.


by: chen
05/25/2012 10:25 AM
I hope the reseach can success. That can help many people who have Alzheimer's .


by: Yoshi from: Sapporo
05/25/2012 2:59 AM
It's nice if the pill which could prevent Alzheimer's disease is developed. Some pills now available are all just only for slowing down its progression for a while.


by: Chieko from: Japan
05/24/2012 10:52 AM
When dementia or Alzheimer's disease reach an advanced stage,some old people come to be unable to eat. In such a case some doctors advised them to do a gastric fistula(gastrostoma). As a result they keep on living until their hearts stand still even if they become a mere vegetable. In Japan once a patient has a gastric fistula, any doctor is unable to get rid of it, because it is a murder. It has become a serious problem in Japan. Every human being has a right to die in peace when the time comes. Does a great advance in medicine bring the elderly people a real happiness?

In Response

by: Ngan Thai from: Vietnam
05/24/2012 3:58 PM
Japan should adopt a law on euthanasia, so terminally ill people would have the option to choose when to die in dignity rather than to continue living in vegetable condition.


by: javier from: colombia
05/24/2012 10:47 AM
Good lock with the reseaches here in colombia, this desease is very important for the health of the people around the world


by: Leo from: Colombia
05/24/2012 2:34 AM
Actually I'm from Medellín Colombia and it's good to hear that people from my region is participating of this kind of experiments, hopefully we will see results in the fight against this devastating illness soon.